Eczema, also known as Atopic Dermatitis (AD), is a chronic inflammatory skin condition that causes red, dry, and intensely itchy patches on the skin1. While it often begins in childhood, AD can persist into adulthood and become a lifelong condition.2
It occurs from a complex interaction of genetic, environmental, and immune-related factors, though its exact cause remains unclear. It is commonly linked with other allergic conditions such as asthma, hay fever, and food allergies. Individuals with eczema often have an overactive immune response that leads to chronic skin inflammation. A key contributor is a mutation in the filaggrin (FLG) gene, which disrupts the production of filaggrin—a protein vital for maintaining the skin’s protective barrier. This deficiency weakens the skin, causing it to lose moisture and become more permeable to irritants, allergens, and microbes, which can trigger immune reactions and worsen symptoms.3
Common symptoms include dry skin, severe nighttime itching, red or brownish-grey patches, small raised bumps, and thickened or cracked skin. Triggers such as dust, certain foods, and emotional stress can worsen symptoms, making daily life challenging.3 Beyond the physical discomfort, eczema can have a profound emotional and psychological impact—affecting sleep, self-esteem, social interactions, and even job performance.
Although there is currently no cure, understanding the condition and managing it through lifestyle changes, trigger avoidance, and proper skincare can significantly improve quality of life for those affected.2
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